Yay! Another Drop 7 believer. The first time I played it took me probably 3 games of losing to finally figure out what the hell was going on too. They should update it with a better tutorial. But once you DO get it you're hooked
Wow, I'm not trying to be mean, but I don't think any of those would be good to play with one hand.... unless you have some sort of special triple joints or maybe a couple extra fingers??? Ok, flick fishing, I could see that.
MotionX Poker and Poker Quest (you could almost play these while driving, better to wait till the car is stopped for a bridge lift), Topple, Tetris, Trism, Geo Defense
For the most part other than flick fishing I sat my itouch on something stationary like a table, desk, and/or on a notepad on my lap...a knee, etc...