Happens on The Today Show too: http://tv.gawker.com/5528012/meredith-viera-says-shit-on-air-while-playing-a-video-game?
The original Space Invaders. Period. In fact, I think I've sworn more at that game over the year on various consoles than I have at any other man-made object. Close second... Ms. Pac Man.
Angry Birds makes me rather angry. Bejeweled 2 makes me go crazy if I lose my Speed Bonus in Bejeweled Blitz (the only mode I play )