I feel like you could lock yourself out from a class (the witch seems like one). However I'm not too sure exactly. Btw the game should take a while to beat. Money doesn't come by easily and the game is actual quite difficult. Also what I just learned is DO NOT go to dungeons you can't beat. You can practically go anywhere on the map however you LOSE money when you die. I'm dirt poor from dying so many times in a row. I believe it's a percentage so the more you have the more you lose.
I generally won't go places until I'm strong enough anyway and I don't find exploring fun usually so will only go places I'm suppose to but still like to check all of those areas when I am there and do any and all side quests. But I do hate it when you lose a percentage of your cash as I usually like to horde my cash!
Nope the items all go away on the continuing playthroughs but on the plus side you get more stat points and more skills! So that'll be great but keeping gear would have been good something like how borderlands works on the +mode although I imagine they have a huge team to make that work! I'm just guessing maybe on your final Playthrough when you have everything just farm the best gear and play endless arena to be the best?
South of Eston is a bandit camp, good for lv5 characters, gives a decent amount of xp, gold and loot. Grinding a few runs there yielded some really good results.Most especially since each run doesnt take too long to complete.
For those who aren't sure if doing an action will change the gameplay.. Quit the game.. Restart upload to cloud then download it back to device if will create another save for u.. I did that for the witch quest.. Speaking of iCloud.. It doesn't seems to able to sync with my iPad.. Haven't really tried but even after uploading to cloud it doesn't show on my iPad